Three types. Different experiences. A shared community.
There are three types of Gaucher disease: type 1, type 2 and type 3.
They share some features, including possible effects on the spleen, liver, blood and bones, but differ in whether and how the brain and nervous system are affected.
Usually does not affect the nervous system. Symptoms can range from very mild to severe.
Research has identified associations between GBA1 variants and Parkinson's disease, and people with Gaucher disease type 1 have been reported to have an increased risk of Parkinson's disease compared with the general population. However, the risk is age-dependent and only a minority of people with Gaucher disease develop Parkinson's disease. Current research continues to investigate the biological mechanisms underlying this association.
People with Gaucher disease also have an increased risk of multiple myeloma, although the reasons for this association are not fully understood.
Gaucher disease does not affect everyone in the same way. The age at which symptoms appear, organs affected, severity and rate of progression can vary considerably, even among people with the same type of Gaucher disease. Some people may have few symptoms, while others require ongoing specialist care for multiple complications. Understanding the type and individual features of Gaucher disease can help healthcare professionals plan appropriate monitoring and care.
Whether you are living with Gaucher disease, caring for someone, or looking for information, this community is here to support you.
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